Opioids have been the mainstay for pain relief and palliation over a long period of time.They are commonly abused by drug Plush Baby addicts and such dependence usually imparts severe physiologic effects on multiple organ systems.The negative impact of opioids on the endocrine system is Pod Vapes poorly understood and often underestimated.
We describe a patient who developed severe suppression of the hypothalamic-pituitary adrenal (HPA) axis leading to secondary adrenal insufficiency due to long standing abuse of opioids.